During its E3 2018 press conference, Bethesda announced Wolfenstein: Youngblood. The sequel follows the events of Wolfenstein II: The New Colossus and is set in the 1980s. It stars series protagonist BJ Blazkowicz's twin daughters, Jessica and Sophia, who are working together to continue the fight against Nazis.
In Youngblood, BJ has gone missing in Nazi-occupied Paris. He narrates the trailer, which shows off the setting and a little bit about Jessica and Sophia. The twins can also be seen wearing the Da'at Yichud armor from Wolfenstein II at the end of the trailer. It's not clear whether Youngblood is the third game in the series--the devs previously stated that they viewed the series as a trilogy--or a separate game in the vein of Wolfenstein: The Old Blood.
Youngblood can be played either solo or co-op and is releasing in 2019. It was announced alongside Wolfenstein: Cyberpilot, a standalone VR game in which you "take control of a fire-breathing Panzerhund and more as you fight Nazis in the City of Love in order to aid the French resistance."